The other day, I had a nosebleed that wouldn't stop. The PI sheet says my new med can interfere with platelets, admittedly not very high on the list of side effects. But I contacted the doc. "Really?" she said, "Where did you hear that was a side effect?" My answer, "On the PI sheet you gave me." It turned out, my blood work was fine, and the humidifier took care of the nosebleeds.
No harm done. Right?
On the other hand, five years ago my GP had me on Prozac. After a couple months, I couldn't sleep, was irritated, agitated, couldn't concentrate, had thoughts of harming myself and others. The PI sheet said I should tell my doctor. My doctor increased the dose.
Thus began a series of antidepressants, and a downward spiral that has ended with disability.